Last names starting with "O"
- Class of 1979 Mike O'Bryan
- Class of 1986 Debra Oakley
- Class of 1960 Elizabeth OBryan
- Class of 1977 Jane OBryan
- Class of 1997 Steve OBryan
- Colleen Oconnor
- Class of 1995 Mark Oetinger
- Class of 2010 Francisco Olague
- Class of 1980 Cheryl Oliver
- Class of 1979 Terri Oneil
- Class of 2009 Maryann Ortega
- Class of 1969 Michael Osborne
- Class of 1975 William Osburn
- Class of 1976 Kathly Owensboro (now Calhoun)
- Class of 1963 Nancy Owensboro,high (now Veal)
- Class of 2009 Keith Owsley
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About the Owensboro High School Alumni Directory
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